Packages used to deliver items or other payloads via a drone may be customized and 3D printed to house the payload. The package may be customized to minimize the size and/or weight needed to house the payload. The customized packages may include one or more attachment mechanisms adapted to engage with or otherwise be coupled to the drone for delivery. Multiple individual customized packages can be secured together into a composite package for delivery by drone. The customized package may be designed to be aerodynamic given the shape of the payload and the flight characteristics of the drone. The drone itself may be the package, with the payload housed within a portion of the drone. The package and/or a portion of the drone (e.g., fuselage, wing, body, frame, etc.) may be printed at least partially in, on, or around an item or package to be transported by the drone.