A long-acting pharmaceutical composition comprising at least one amphetamine salt is provided. The composition comprises an immediate release component, a delayed release component, and a sustained release component comprising one or more amphetamine salts. The sustained release component comprises a sustained release layer and a delayed release layer, such that the delayed release layer is coated onto the sustained release layer. The time (Tmax) to achieve Cmax after administration of said composition is between 7-10 hours.