- 专利标题： PHARMACEUTICAL COMPOSITIONS AND ADMINISTRATIONS THEREOF
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申请号： US15643182申请日： 2017-07-06
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公开(公告)号： US20180153874A1公开(公告)日： 2018-06-07
- 发明人: Fredrick F. Van Goor , Rossitza Gueorguieva Alargova , Tim Edward Alcacio , Sneha G. Arekar , Steven C. Johnston , Irina Nicolaevna Kadiyala , Ali Keshavarz-Shokri , Mariusz Krawiec , Elaine Chungmin Lee , Ales Medek , Praveen Mudunuri , Mark Jeffrey Sullivan , Noreen Tasneem Zaman , Beili Zhang , Yuegang Zhang , Gregor Zlokarnik
- 申请人： Vertex Pharmaceuticals Incorporated
- 申请人地址： US MA Boston
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： US MA Boston
- 主分类号： A61K31/47
- IPC分类号： A61K31/47 ; A61K31/443 ; A61K31/4433 ; A61K31/4704 ; A61K31/404 ; G01N33/50
摘要：
The present invention relates to pharmaceutical compositions comprising a compound of Formula I in combination with one or both of a Compound of Formula II and/or a Compound of Formula III. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis.
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