- 专利标题： A METHOD OF PREDICTING RISK OF RECURRENCE OF CANCER
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申请号： US15511890申请日： 2015-09-18
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公开(公告)号： US20180148788A1公开(公告)日： 2018-05-31
- 发明人: Adrian BRACKEN , Fiona LANIGAN , William GALLAGHER
- 申请人： THE PROVOST, FELLOWS, SCHOLARS AND OTHER MEMBERS OF BOARD OF TRINITY COLLEGE DUBLIN , UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
- 申请人地址： IE Dublin IE Dublin
- 专利权人： THE PROVOST, FELLOWS, SCHOLARS AND OTHER MEMBERS OF BOARD OF TRINITY COLLEGE DUBLIN,UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
- 当前专利权人： THE PROVOST, FELLOWS, SCHOLARS AND OTHER MEMBERS OF BOARD OF TRINITY COLLEGE DUBLIN,UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
- 当前专利权人地址： IE Dublin IE Dublin
- 优先权： EP14185673.2 20140919
- 国际申请： PCT/EP2015/071524 WO 20150918
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; G01N33/574 ; A61K31/519
摘要：
A method for predicting risk of recurrence of cancer in an individual with cancer, the method comprising a step of assaying a cancer sample from the individual for positive expression of at least two genes or proteins encoded by those genes selected from the group consisting of FOXM1, UHRF1, PTTG1, E2F1, MYBL2, HMGB2, ATAD2, E2F8, ZNF367 and TCF19, wherein positive expression of the at least two genes correlates with increased risk of recurrence of cancer compared with an individual who does not exhibit positive expression of the at least two genes or proteins encoded by those genes.
公开/授权文献
- US10557175B2 Method of predicting risk of recurrence of cancer 公开/授权日：2020-02-11
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