Invention Application
- Patent Title: COMPOSITIONS AND METHODS OF USING CHONDROITINASE ABCI MUTANTS
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Application No.: US15789384Application Date: 2017-10-20
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Publication No.: US20180066245A1Publication Date: 2018-03-08
- Inventor: Anthony O. CAGGIANO , Jennifer IACI , Andrea VECCHIONE , Elizabeth HUNTER
- Applicant: Acorda Therapeutics, Inc.
- Main IPC: C12N9/88
- IPC: C12N9/88 ; A61K38/51 ; A61K38/00
Abstract:
One aspect of the present invention relates to mutants of chondroitinase ABCI. Such chondroitinase ABCI mutants exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including exposure to UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.
Public/Granted literature
- US10323240B2 Compositions and methods of using chondroitinase ABCI mutants Public/Granted day:2019-06-18
Information query
