Invention Application
- Patent Title: PYRROLIDINE AMIDE COMPOUNDS AS HISTONE DEMETHYLASE INHIBITORS
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Application No.: US15482584Application Date: 2017-04-07
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Publication No.: US20170312252A1Publication Date: 2017-11-02
- Inventor: Kwong Wah Lai , Jun Liang , Birong Zhang , Sharada Labadie , Daniel Ortwine , Peter Dragovich , James Kiefer , Victor S. Gehling , Jean-Christophe Harmange
- Applicant: GENENTECH, INC. , CONSTELLATION PHARMACEUTICALS, INC.
- Priority: CNPCT/CN2014/088309 20141010
- Main IPC: A61K31/41
- IPC: A61K31/41 ; A61K31/4025 ; C07D207/04 ; C07D237/04
Abstract:
The present invention relates to compounds useful as inhibitors of one or more histone demethylses, such as KDM5. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
Public/Granted literature
- US10022354B2 Pyrrolidine amide compounds as histone demethylase inhibitors Public/Granted day:2018-07-17
Information query
