A system and method for rapid pressurization of a motor compartment and cooling system during a shutdown, a surge, and/or other situations in which the suction pressure significantly varies. A motor/compressor arrangement includes a seal gas system fluidly communicating with the motor compartment via a motor pressurization line, with the outlet of the compressor, and with a shaft seal. A motor pressurization valve is coupled to the motor pressurization line and a controller is configured to open the motor pressurization valve at start-up of the motor-compressor to supply seal gas to the motor compartment and to pressurize the motor compartment when a difference between the seal gas supply pressure and the suction pressure is indicative of the seal gas supply pressure being insufficient.