Invention Application
- Patent Title: REAGENTS AND METHODS FOR DETECTING PNH TYPE II WHITE BLOOD CELLS AND THEIR IDENTIFICATION AS RISK FACTORS FOR THROMBOTIC DISORDERS
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Application No.: US15591531Application Date: 2017-05-10
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Publication No.: US20170285013A1Publication Date: 2017-10-05
- Inventor: Mayur MOVALIA , Andrea ILLINGWORTH , Susan Faas MCKNIGHT , Russell P. ROTHER
- Applicant: Alexion Pharmaceuticals, Inc.
- Main IPC: G01N33/50
- IPC: G01N33/50 ; G01N33/68 ; C07K16/40 ; A61K38/48 ; A61K38/19 ; G01N33/569 ; A61K31/727 ; A61K31/56 ; A61K31/352 ; A61K35/19
Abstract:
The disclosure relates to methods for detecting PNH Type II cell populations in biological samples as well as methods for determining whether a patient is at an increased risk for developing thrombocytopenia or thrombosis based on the percentage of PNH Type II cells in the patient's blood. The disclosure also features reagents and conjugates for use in the methods.
Public/Granted literature
Information query
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