A spindle drive for an adjustment element of a motor vehicle is provided. The spindle drive has a drive unit and a spindle-spindle nut transmission arranged downstream of the drive unit in terms of drive for generating linear drive movements. The drive unit has a tubular drive unit housing and therein a drive motor. In some cases an intermediate transmission is arranged downstream of the drive motor in terms of drive. The drive unit and the spindle-spindle nut transmission are arranged one behind the other on the geometrical spindle axis, and a spindle drive housing is provided with a tubular inner housing and a tubular outer housing. The inner housing runs in a telescope-like manner in the outer housing. In some cases the outer housing of the spindle drive housing accommodates the drive unit with the drive unit housing and is connected to the drive unit.