Golf ball having at least three layers comprising ionomeric and/or HNP compositions, wherein for each two adjacent layers, a relationship is established between a ratio of the volumes of the two adjacent layers and a ratio of the percent neutralizations of those two layers such that the volumes and % neutralizations of all layers are interrelated and interdependent to produce unique and desirable playing characteristics. In one embodiment, a golf ball of the invention has T layers, wherein T≧3 and each of T layers has a different volume “V” and comprises an ionomeric and/or HNP composition having a different % neutralization “N”; and wherein each of n inner layers of the T layers (n