- 专利标题： METHODS AND FORMULATION FOR IMPROVING ORAL AVAILABILITY OF CPT-11 WHILE REDUCING CPT-11 INDUCED GASTROINTESTINAL TOXICITY IN CANCER THERAPY
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申请号： US15519559申请日： 2015-10-21
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公开(公告)号： US20170246190A1公开(公告)日： 2017-08-31
- 发明人: Pei-Ru LIAO , Kwan-Hwa CHI
- 申请人： Johnpro Biotech Inc.
- 申请人地址： TW Taipei City
- 专利权人： Johnpro Biotech Inc.
- 当前专利权人： Johnpro Biotech Inc.
- 当前专利权人地址： TW Taipei City
- 国际申请： PCT/CN2015/092401 WO 20151021
- 主分类号： A61K31/575
- IPC分类号： A61K31/575 ; A61K31/4745 ; A61K36/28 ; A61K31/353
摘要：
Disclosed herein are methods and formulation for enhancing oral availability of CPT-11 during cancer therapy while at the same time, reducing its gastrointestinal (GI) toxicity, thus the methods and formulations as disclosed herein may augment the efficacy of cancer therapy.
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