发明申请
- 专利标题： LIVER-SPECIFIC NUCLEIC ACID REGULATORY ELEMENTS AND METHODS AND USE THEREOF
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申请号： US15483958申请日： 2017-04-10
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公开(公告)号： US20170209600A1公开(公告)日： 2017-07-27
- 发明人: Marinee Chuah , Thierry Vandendriessche , Pieter De Bleser
- 申请人： VIB VZW , Life Sciences Research Partners VZW , Universiteit Gent
- 申请人地址： BE Gent BE Leuven BE Gent
- 专利权人： VIB VZW,Life Sciences Research Partners VZW,Universiteit Gent
- 当前专利权人： VIB VZW,Life Sciences Research Partners VZW,Universiteit Gent
- 当前专利权人地址： BE Gent BE Leuven BE Gent
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C12N9/64 ; C12N15/86 ; A61K38/48
摘要：
Described are nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. These are particularly useful for applications using gene therapy.
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