Invention Application
US20170073340A1 SUBSTITUTED CYCLOPENTANES, TETRAHYDROFURANES AND PYRROLIDINES AS OREXIN RECEPTOR ANTAGONISTS
有权
取代环孢菌素，四氢呋喃和吡咯烷作为OREXIN受体拮抗剂
- Patent Title: SUBSTITUTED CYCLOPENTANES, TETRAHYDROFURANES AND PYRROLIDINES AS OREXIN RECEPTOR ANTAGONISTS
- Patent Title (中): 取代环孢菌素，四氢呋喃和吡咯烷作为OREXIN受体拮抗剂
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Application No.: US15120002Application Date: 2015-02-19
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Publication No.: US20170073340A1Publication Date: 2017-03-16
- Inventor: Charlotte Fieldhouse , Angela Glen , Tatsuhiko Fujimoto , John Stephen Robinson
- Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Applicant Address: JP Osaka-shi
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka-shi
- Priority: EP14156010.2 20140220
- International Application: PCT/GB2015/050482 WO 20150219
- Main IPC: C07D417/14
- IPC: C07D417/14 ; A61K31/4439 ; A61K31/4709 ; A61K31/4545 ; C07D401/12 ; A61K31/498 ; C07D417/12 ; C07D413/12
Abstract:
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, Formula (I) wherein L, X, Ra, Rb, R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
Public/Granted literature
- US09790220B2 Substituted cyclopentanes, tetrahydrofuranes and pyrrolidines as orexin receptor antagonists Public/Granted day:2017-10-17
Information query
