Provided are compositions comprising an orally acceptable carrier, an extract of Myristica fragrans derived from nutmeg or mace, and an extract of Vaccinium subgenus Oxycoccus. The compositions may also include an extract of neem and Competence Stimulating Peptide (CSP). Also provided is a method for inhibiting the growth of Streptococcus mutans in a biofilm in the oral cavity of a subject, the method comprising administering to the oral cavity of the subject a composition comprising an orally acceptable carrier, an extract of Myristica fragrans derived from nutmeg or mace, an extract of Vaccinium subgenus Oxycoccus, wherein administering the composition selectively inhibits the rate of growth of Streptococcus mutans over the rate of growth of at least one species of non-Streptococcus mutans bacteria in the biofilm.