Disclosed herein is method of performing self-interference cancellation in the network nodes supporting full-duplex communication. Specifically, the method includes receiving a desired signal from a user equipment (UE), performing cancellation of self-interference according to a transmitted signal of the network node, the transmitted signal using the same radio resource as the desired signal, determining whether the cancellation of the self-interference is successful, performing, upon determining that the cancellation of the self-interference is successful, decoding of the desired signal and checking cyclic redundancy check (CRC), and performing power control and link adaptation depending on success in performing the cancellation of the self-interference and a result of checking the CRC.