发明申请
- 专利标题： Imidazopyridine Derivatives as Modulators of TNF Activity
- 专利标题（中）： 咪唑并吡啶衍生物作为TNF活性的调节剂
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申请号： US15038555申请日： 2014-12-08
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公开(公告)号： US20160355509A1公开(公告)日： 2016-12-08
- 发明人: Victoria Elizabeth Jackson , Boris Kroeplien , John Robert Porter
- 申请人： UCB BIOPHARMA SPRL
- 优先权： GB1321735.1 20131209
- 国际申请： PCT/EP2014/076837 WO 20141208
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K31/444 ; A61K31/437
摘要：
A series of substituted 3H-imidazo[4,5-c]pyridine derivatives of formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
公开/授权文献
- US09890154B2 Imidazopyridine derivatives as modulators of TNF activity 公开/授权日：2018-02-13
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