Invention Application
- Patent Title: BENZIMIDAZOLE AND IMADAZOPYRIDINE CARBOXIMIDAMIDE COMPOUNDS
- Patent Title (中): 苯并咪唑和甲基嘧啶羧酰胺化合物
-
Application No.: US15153527Application Date: 2016-05-12
-
Publication No.: US20160333009A1Publication Date: 2016-11-17
- Inventor: Mark J. Bartlett , Julian Andrew Codelli , Britton Kenneth Corkey , Jennifer Leigh Cosman , Kristyna Elbel , Jennifer Alissa Loyer-Drew , David Sperandio , Joshua Van Veldhuizen , Hai Yang , Suet Chung Yeung
- Applicant: Gilead Sciences, Inc.
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D235/08 ; A61K31/4184 ; A61K31/5377 ; C07D401/12 ; A61K31/454 ; A61K31/437 ; A61K31/506 ; A61K31/497 ; A61K31/55 ; A61K31/541 ; A61K31/439 ; C07D405/12 ; C07D405/14 ; C07D471/08 ; A61K31/553 ; C07D235/30 ; C07D235/14 ; C07D401/04 ; C07D235/12 ; A61K31/444 ; A61K31/4545 ; A61K31/538 ; A61K31/5386 ; A61K31/438 ; C07D403/12 ; A61K31/4439 ; C07D235/24 ; C07D413/12 ; A61K31/496 ; C07D487/04 ; A61K31/4725 ; C07D235/28 ; A61K45/06

Abstract:
The present disclosure provides indoleamine 2,3-dioxygenase 1 (IDOL) inhibitors of Formula I: or pharmaceutically acceptable salts thereof, in which X, L, n, m, R1, R2a, R2b, Rn, Rm, and Rt are as defined herein, as well as pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using the same to treat conditions mediated by IDO1.
Public/Granted literature
- US09951065B2 Benzimidazole and imadazopyridine carboximidamide compounds Public/Granted day:2018-04-24
Information query