- 专利标题： Antibody Glycosylation Variants Having Increased Antibody-Dependent Cellular Cytotoxicity
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申请号： US15080020申请日： 2016-03-24
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公开(公告)号： US20160272719A1公开(公告)日： 2016-09-22
- 发明人: Pablo Umaña , Joël Jean-Mairet , James E. Bailey
- 申请人： Roche GlycArt AG
- 申请人地址： CH Schlieren-Zurich
- 专利权人： Roche GlycArt AG
- 当前专利权人： Roche GlycArt AG
- 当前专利权人地址： CH Schlieren-Zurich
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C07K16/30
摘要：
The present invention relates to the field of glycosylation engineering of proteins. More particularly, the present invention relates to glycosylation engineering to generate proteins with improved therapeutic properties, including antibodies with increased antibody-dependent cellular cytotoxicity.
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