Invention Application
US20160185787A1 NEW STABLE SALT OF 5,10-METHYLENE-(6R)-TETRAHYDROFOLIC ACID
审中-公开
新的稳定的5,10-甲基 - （6R） - 异佛尔酮酸
- Patent Title: NEW STABLE SALT OF 5,10-METHYLENE-(6R)-TETRAHYDROFOLIC ACID
- Patent Title (中): 新的稳定的5,10-甲基 - （6R） - 异佛尔酮酸
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Application No.: US14912328Application Date: 2014-08-14
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Publication No.: US20160185787A1Publication Date: 2016-06-30
- Inventor: Rudolf MOSER , Viola GROEHN , Thomas EGGER , Thomas AMMANN
- Applicant: MERCK & CIE
- Applicant Address: CH Schaffhausen
- Assignee: MERCK & CIE
- Current Assignee: MERCK & CIE
- Current Assignee Address: CH Schaffhausen
- Priority: EP13004050.4 20130814
- International Application: PCT/EP2014/067447 WO 20140814
- Main IPC: C07D487/14
- IPC: C07D487/14
Abstract:
The present invention is directed towards the hemisulfate salt of 5,10-methylene-(6R)-tetrahydrofolic acid, preferably in substantially crystalline form, as well as pharmaceutical compositions and uses thereof in therapy, preferably chemotherapy.
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