Invention Application
- Patent Title: AROMATIC COMPOUND
- Patent Title (中): 芳香化合物
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Application No.: US14898633Application Date: 2014-08-08
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Publication No.: US20160115128A1Publication Date: 2016-04-28
- Inventor: Jumpei AIDA , Yayoi YOSHITOMI , Yuko HITOMI , Naoyoshi NOGUCHI , Yasuhiro HIRATA , Hideki FURUKAWA , Akito SHIBUYA , Koji WATANABE , Yasufumi MIYAMOTO , Tomohiro OKAWA , Nobuyuki TAKAKURA , Seiji MIWATASHI
- Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Applicant Address: JP Osaki-shi, Osaka
- Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee Address: JP Osaki-shi, Osaka
- Priority: JP2013-167065 20130809
- International Application: PCT/JP2014/070972 WO 20140808
- Main IPC: C07D211/34
- IPC: C07D211/34 ; C07D413/10 ; C07D401/14 ; C07D405/12 ; C07D413/14 ; C07D401/10 ; C07D401/12

Abstract:
Provided is a novel aromatic ring compound having a GPR40 agonist activity and a GLP-1 secretagogue action. A compound represented by the formula: wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a GPR40 agonist activity and a GLP-1 secretagogue action, is useful for the prophylaxis or treatment of cancer, obesity, diabetes, hypertension, hyperlipidemia, cardiac failure, diabetic complications, metabolic syndrome, sarcopenia and the like, and affords superior efficacy.
Public/Granted literature
- US09776962B2 Aromatic compounds with GPR40 agonistic activity Public/Granted day:2017-10-03
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