发明申请
- 专利标题: 19-NOR NEUROACTIVE STEROIDS AND METHODS OF USE THEREOF
- 专利标题(中): 19-NOR神经营养甾体及其使用方法
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申请号: US14785162申请日: 2014-04-17
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公开(公告)号: US20160068563A1公开(公告)日: 2016-03-10
- 发明人: Gabriel Martinez Botella , Boyd L. Harrison , Albert Jean Robichaud , Francesco G. Salituro , Richard Thomas Beresis
- 申请人: Boyd L. HARRISON , Albert Jean ROBICHAUD , Francesco g. SALITURO , Richard Thomas BERESIS
- 优先权: CNPCT/CN2013/074319 20130417
- 国际申请: PCT/CN2014/075600 WO 20140417
- 主分类号: C07J43/00
- IPC分类号: C07J43/00
摘要:
Provided herein are 3,3-disubstituted 19-nor-steroidal compounds according to Formula (I): and pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, tinnitus, status epilepticus.
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