A self-powered wireless mouse apparatus includes a mouse wheel module and a back-end processing module. The mouse wheel module includes a mouse wheel, a stator plate, a plurality of coils and a rotation shaft. The mouse wheel includes a multipolar magnetic body. The coils are arranged on the stator plates. The rotation shaft is connected to the mouse wheel and the stator plate. The back-end processing module includes an alternating current to direct current conversion circuit and an energy storing apparatus. The multipolar magnetic body is driven so that the coils generate induced alternating current voltages when the mouse wheel is rotated. The alternating current to direct current conversion circuit converts the induced alternating current voltages of the coils into direct current voltages and then stores the direct current voltages in the energy storing apparatus to supply power to the self-powered wireless mouse apparatus.