发明申请
US20160039817A1 TRIAZOLOPYRIDYL COMPOUNDS AS ALDOSTERONE SYNTHASE INHIBITORS
审中-公开
三唑酮化合物作为醛固酮合成酶抑制剂
- 专利标题： TRIAZOLOPYRIDYL COMPOUNDS AS ALDOSTERONE SYNTHASE INHIBITORS
- 专利标题（中）： 三唑酮化合物作为醛固酮合成酶抑制剂
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申请号： US14886563申请日： 2015-10-19
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公开(公告)号： US20160039817A1公开(公告)日： 2016-02-11
- 发明人: D. Jonathan Bennett , Jaiqiang Cai , Emma Carswell , Andrew Cooke , Scott B. Hoyt , Clare London , John MacLean , Paul Ratcliffe , Jerry Andrew Taylor , Yusheng Xiong , Swapan Kumar Samanta , Bheemashankar A. Kulkarni
- 申请人： Merck Sharp & Dohme Corp.
- 主分类号： C07D471/04
- IPC分类号： C07D471/04
摘要：
This invention relates to triazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
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