Invention Application
US20150284382A1 HETEROARYL SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS
有权
异氟醚取代的吡啶化合物可用作激酶调节剂
- Patent Title: HETEROARYL SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS
- Patent Title (中): 异氟醚取代的吡啶化合物可用作激酶调节剂
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Application No.: US14441705Application Date: 2013-11-07
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Publication No.: US20150284382A1Publication Date: 2015-10-08
- Inventor: Rajeev S. Bhide , John V. Duncia , John Hynes , Satheesh K. Nair , William J. Pitts , Sreekantha R. Kumar , Daniel S. Gardner , Natesan Murugesan , Venkatram Reddy Paidi , Joseph B. Santella , Ramesh Sistla , Hong Wu
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- International Application: PCT/US2013/068875 WO 20131107
- Main IPC: C07D417/14
- IPC: C07D417/14 ; C07D401/14 ; C07D405/12 ; C07D405/14 ; C07D213/74 ; C07D401/12
Abstract:
Compounds having the following formula (I) or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R2 is a monocyclic heteroaryl group, and R1, R3, R4, R5 and R6 are as defined herein, are useful as kinase modulators, including IRAK-4 inhibition.
Public/Granted literature
- US09657009B2 Heteroaryl substituted pyridyl compounds useful as kinase modulators Public/Granted day:2017-05-23
Information query
