A method of laying a pipeline from a laying vessel into a body of water includes guiding the pipeline along a supporting structure of a laying ramp. The method also includes acquiring a first data item correlated to a position of the pipeline at a free end of the laying ramp using an optical sensor or an acoustic sensor. The method further includes determining whether the acquired first data item is within an acceptance range predetermined as a function of a configuration of the supporting structure and a size of the pipeline. Additionally, the method includes emitting an control signal when the acquired first data item is not within the acceptance range. Determining whether the acquired first data item is within the acceptance range includes processing the acquired first data item to compare it the first data item to an information stored in a memory.