发明申请
- 专利标题： Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells
- 专利标题（中）： 使用化合物诱导间充质干细胞分化为软骨细胞
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申请号： US14720479申请日： 2015-05-22
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公开(公告)号： US20150252003A1公开(公告)日： 2015-09-10
- 发明人: Ki Chul Hwang , Yang Soo Jang , Gyoon Hee Han
- 申请人： Industry-Academic Cooperation Foundation, Yonsei University
- 优先权： KR10-2010-0091081 20100916
- 主分类号： C07D215/36
- IPC分类号： C07D215/36 ; A61K35/32 ; C07C311/17 ; C07C311/20 ; C12N5/077 ; C07C311/21
摘要：
Use of a compound of Formula 1 for inducing differentiation of mesenchymal stem cells to chondrocytes, and a pharmaceutical composition for treating a cartilage disease, which includes chondrocytes in which differentiation from mesenchymal stem cells is induced by the compound of Formula 1, are provided. Differentiation of the mesenchymal stem cells treated with the compound of Formula 1 to chondrocytes is specifically induced, and thus the compound can be used to effectively treat a cartilage disease such as arthritis, cartilage damage, and a cartilage defect.
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