Invention Application
- Patent Title: EXPANDING THE EUKARYOTIC GENETIC CODE
- Patent Title (中): 扩展“原始遗传代码”
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Application No.: US14574257Application Date: 2014-12-17
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Publication No.: US20150240249A1Publication Date: 2015-08-27
- Inventor: Jason W. Chin , T. Ashton Cropp , J. Christopher Anderson , Peter G. Schultz
- Applicant: The Scripps Research Institute
- Main IPC: C12N15/81
- IPC: C12N15/81 ; C12N9/00
Abstract:
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
Public/Granted literature
- US09580721B2 Expanding the eukaryotic genetic code Public/Granted day:2017-02-28
Information query
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