发明申请
- 专利标题： Selective PYY compounds and uses thereof
- 专利标题（中）： 选择性PYY化合物及其用途
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申请号： US14540474申请日： 2014-11-13
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公开(公告)号： US20150152150A1公开(公告)日： 2015-06-04
- 发明人: Soeren Oestergaard , Kilian Waldemar Conde Frieboes , Birgit Wieczorek , Jens Kaalby Thomsen , Birgitte Schjellerup Wulff , Carsten Jessen
- 申请人： Novo Nordisk A/S
- 优先权： EP13193082.8 20131115; EP14176725.1 20140711
- 主分类号： C07K14/47
- IPC分类号： C07K14/47 ; A61K45/06 ; A61K38/17
摘要：
The invention relates to PYY compounds having the amino acid in the position corresponding to position 30 of hPYY(1-36) substituted with tryptophan and derivatives thereof with a modifying group attached to the position corresponding to position 7 of hPYY(1-36). The compounds of the invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as the medical use of the PYY compounds.
公开/授权文献
- US09085637B2 Selective PYY compounds and uses thereof 公开/授权日：2015-07-21
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