发明申请
- 专利标题: EXPANSION OF ALLOANTIGEN-REACTIVE REGULATORY T CELLS
- 专利标题(中): 细胞增殖调节细胞的扩增
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申请号: US14382537申请日: 2013-03-01
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公开(公告)号: US20150110761A1公开(公告)日: 2015-04-23
- 发明人: Qizhi Tang , Jeffrey A. Bluestone
- 申请人: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- 国际申请: PCT/US2013/028734 WO 20130301
- 主分类号: A61K35/17
- IPC分类号: A61K35/17 ; C12N5/0783
摘要:
The present disclosure relates generally to the manufacture of regulatory T cells (Tregs) for use in immunotherapy. In particular, the present disclosure relates to robust approaches for the expansion of alloantigen-reactive Tregs ex vivo. Alloantigen-reactive Tregs produced in this way are suitable for the induction and/or maintenance of immunologic tolerance in recipients of allogeneic transplants.
公开/授权文献
- US09801911B2 Expansion of alloantigen-reactive regulatory T cells 公开/授权日:2017-10-31
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