发明申请
US20150017231A1 POLYAMINE TRANSPORT SELECTIVE THERAPEUTIC AGENTS WITH ENHANCED STABILITY
有权
聚氨酯运输选择性治疗药物具有增强的稳定性
- 专利标题： POLYAMINE TRANSPORT SELECTIVE THERAPEUTIC AGENTS WITH ENHANCED STABILITY
- 专利标题（中）： 聚氨酯运输选择性治疗药物具有增强的稳定性
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申请号： US14388856申请日： 2013-03-14
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公开(公告)号： US20150017231A1公开(公告)日： 2015-01-15
- 发明人: Otto Phanstiel, IV , Aaron Muth
- 申请人： UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION. INC.
- 申请人地址： US FL Orlando
- 专利权人： University of Central Florida Research Foundation, Inc.
- 当前专利权人： University of Central Florida Research Foundation, Inc.
- 当前专利权人地址： US FL Orlando
- 国际申请： PCT/US13/31166 WO 20130314
- 主分类号： C07C211/31
- IPC分类号： C07C211/31 ; C07C211/27 ; C07C211/30 ; A61K31/138
摘要：
Disclosed herein are di-substituted aryl polyamine compounds and methods of making and using the same. The di-substituted polyamine compounds act as PTS targeting agents, which selectively target the polyamine transport system (PTS) with high efficacy and have improved stability in the presence of amine oxidases.
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