Invention Application
- Patent Title: Heterocyclic Compounds and Methods of Their Use
- Patent Title (中): 杂环化合物及其使用方法
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Application No.: US14370737Application Date: 2013-01-04
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Publication No.: US20140378430A1Publication Date: 2014-12-25
- Inventor: Thomas David McCarthy , Alan Naylor
- Applicant: Spinifex Pharmaceuticals Pty Ltd
- Applicant Address: AU Preston Victoria
- Assignee: SPINIFEX PHARMACEUTICALS PTY LTD
- Current Assignee: SPINIFEX PHARMACEUTICALS PTY LTD
- Current Assignee Address: AU Preston Victoria
- Priority: AU2012900057 20120106
- International Application: PCT/AU2013/000003 WO 20130104
- Main IPC: C07D498/10
- IPC: C07D498/10 ; C07D209/42 ; C07D413/04 ; C07D401/04 ; C07D403/04 ; C07D401/12 ; C07D409/04 ; C07D205/04 ; C07D207/14 ; C07D207/16 ; C07D471/10
Abstract:
The present invention relates to heterocyclic compounds useful for antagonising angiotensin II Type 2 (AT2) receptor. More particularly the invention relates to pyrrolidine and azetidine compounds, compositions containing them and their use in methods of treating or preventing disorders or diseases associated with AT2 receptor function including neuropathic pain, inflammatory pain, conditions associated with neuronal hypersensitivity, impaired nerve conduction velocity, cell proliferation disorders, disorders associated with an imbalance between bone resorption and bone formation and disorders associated with aberrant nerve regeneration.
Public/Granted literature
- US09624243B2 Heterocyclic compounds and methods of their use Public/Granted day:2017-04-18
Information query
