Invention Application
US20140350115A1 POLYMORPHS OF N-MALONYL-BIS(N`-METHYL-N`-THIOBENZOYLHYDRAZIDE)
审中-公开
N-马来酰亚胺（N，N'-甲基-N'-噻唑烷基硫化物）的聚合物
- Patent Title: POLYMORPHS OF N-MALONYL-BIS(N`-METHYL-N`-THIOBENZOYLHYDRAZIDE)
- Patent Title (中): N-马来酰亚胺（N，N'-甲基-N'-噻唑烷基硫化物）的聚合物
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Application No.: US14165448Application Date: 2014-01-27
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Publication No.: US20140350115A1Publication Date: 2014-11-27
- Inventor: Elena Kostik , Lijun Sun , Joanna Dziewiszek , Jun Y. Choi
- Applicant: SYNTA PHARMACEUTICALS CORP.
- Applicant Address: US MA Lexington
- Assignee: SYNTA PHARMACEUTICALS CORP.
- Current Assignee: SYNTA PHARMACEUTICALS CORP.
- Current Assignee Address: US MA Lexington
- Main IPC: C07C327/56
- IPC: C07C327/56
Abstract:
At least 70% by weight of Compound 1 is the single crystalline form, Form A, Form C, or Form D, of the compound. A pharmaceutical composition comprises a pharmaceutically acceptable carrier or diluent, and compound 1, wherein at least 70% by weight of the compound is the single crystalline form, Form A, Form C, or Form D, of the compound. A method of treating a subject with cancer comprises administering to the subject an effective amount of compound 1 or the pharmaceutical composition.
Public/Granted literature
- US09051250B2 Polymorphs of N-malonyl-bis(N′-methyl-N′-thiobenzoylhydrazide) Public/Granted day:2015-06-09
Information query
