发明申请
US20140302082A1 NUCLEIC ACID CONSTRUCT COMPRISING NUCLEIC ACID DERIVED FROM GENOME OF HEPATITIS C VIRUS OF GENOTYPE 1B, HEPATITIS C VIRUS GENOME-REPLICATING CELLS TRANSFECTED WITH THE SAME, AND METHOD FOR PRODUCING INFECTIOUS HEPATITIS C VIRUS PARTICLES
有权
含有基因组1B的乙型肝炎病毒C型病毒基因组的核酸构建体，与其转染的丙型肝炎病毒基因组代谢细胞及其生产感染性丙型肝炎病毒颗粒的方法
- 专利标题： NUCLEIC ACID CONSTRUCT COMPRISING NUCLEIC ACID DERIVED FROM GENOME OF HEPATITIS C VIRUS OF GENOTYPE 1B, HEPATITIS C VIRUS GENOME-REPLICATING CELLS TRANSFECTED WITH THE SAME, AND METHOD FOR PRODUCING INFECTIOUS HEPATITIS C VIRUS PARTICLES
- 专利标题（中）： 含有基因组1B的乙型肝炎病毒C型病毒基因组的核酸构建体，与其转染的丙型肝炎病毒基因组代谢细胞及其生产感染性丙型肝炎病毒颗粒的方法
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申请号： US14009049申请日： 2012-03-30
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公开(公告)号： US20140302082A1公开(公告)日： 2014-10-09
- 发明人: Takaji Wakita , Tomoko Date , Yasuhito Tanaka , Masashi Mizokami
- 申请人： Takaji Wakita , Tomoko Date , Yasuhito Tanaka , Masashi Mizokami
- 申请人地址： JP Tokyo JP Nagoya-shi, Aichi JP Tokyo
- 专利权人： JAPAN AS REPRESENTED BY DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASE,PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY,TORAY INDUSTRIES, INC.
- 当前专利权人： JAPAN AS REPRESENTED BY DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASE,PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY,TORAY INDUSTRIES, INC.
- 当前专利权人地址： JP Tokyo JP Nagoya-shi, Aichi JP Tokyo
- 优先权： JP2011-080678 20110331
- 国际申请： PCT/JP2012/058516 WO 20120330
- 主分类号： C12N7/00
- IPC分类号： C12N7/00 ; C12Q1/70 ; C07K16/08
摘要：
A subgenomic replicon RNA (nucleic acid) having an excellent autonomously replicating ability and a fullgenomic replicon RNA (nucleic acid) having an excellent autonomously replicating ability and infectious HCV particle-producing ability, each derived from a novel HCV of genotype 1b, are provided. Particularly, a subgenomic replicon RNA (nucleic acid) and a fullgenomic replicon RNA (nucleic acid), each derived from an HCV genome of the NC1 strain which is a novel HCV genotype 1b isolated from a patient with acute severe hepatitis C, are provided.
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