发明申请
US20140271684A1 PD-1 ANTIBODIES IN COMBINATION WITH A CYTOKINE-SECRETING CELL AND METHODS OF USE THEREOF
审中-公开
与细胞因子分泌细胞组合的PD-1抗体及其使用方法
- 专利标题： PD-1 ANTIBODIES IN COMBINATION WITH A CYTOKINE-SECRETING CELL AND METHODS OF USE THEREOF
- 专利标题（中）： 与细胞因子分泌细胞组合的PD-1抗体及其使用方法
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申请号： US14078042申请日： 2013-11-12
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公开(公告)号： US20140271684A1公开(公告)日： 2014-09-18
- 发明人: Betty LI , Karin JOOSS , Alan J. KORMAN
- 申请人： Medarex, Inc. , ADURO GVAX INC.
- 申请人地址： US CA Milpitas US CA Berkeley
- 专利权人： Medarex, Inc.,ADURO GVAX INC.
- 当前专利权人： Medarex, Inc.,ADURO GVAX INC.
- 当前专利权人地址： US CA Milpitas US CA Berkeley
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K38/19
摘要：
The present invention relates to a method of enhancing the anti-tumor response in a mammal. More particularly, the invention is concerned with combinations comprising a cytokine-secreting cell and an anti-PD-1 antibody, and methods of administering the combination for enhanced immune response to tumor cells in a patient with a cancer.
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