发明申请
- 专利标题： IDENTIFICATION OF A JAK2 MUTATION IN POLYCYTHEMIA VERA
- 专利标题（中）： 鉴定在多聚乙烯VERA中的JAK2突变
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申请号： US14164880申请日： 2014-01-27
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公开(公告)号： US20140249204A1公开(公告)日： 2014-09-04
- 发明人: William Vainchenker , Valeria Ugo , James Chloe , Jean-Pierre Le Couedic , Nicole Casadevall
- 申请人： Institut Gustave-Roussy , Institut National De La Sante Et De La Rechereche Scientifique (Inserm) , Universite Paris-Sud , Universite De Versailles - St Quentin En Yvelines , Assistance Publique-Hopitaux De Paris
- 申请人地址： FR Villejuif FR Paris FR Orsay FR Versailles FR Paris
- 专利权人： Institut Gustave-Roussy,Institut National De La Sante Et De La Rechereche Scientifique (Inserm),Universite Paris-Sud,Universite De Versailles - St Quentin En Yvelines,Assistance Publique-Hopitaux De Paris
- 当前专利权人： Institut Gustave-Roussy,Institut National De La Sante Et De La Rechereche Scientifique (Inserm),Universite Paris-Sud,Universite De Versailles - St Quentin En Yvelines,Assistance Publique-Hopitaux De Paris
- 当前专利权人地址： FR Villejuif FR Paris FR Orsay FR Versailles FR Paris
- 优先权： FR0411480 20041027
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12N15/113
摘要：
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative disorders, or to the detection of the JAK2 V617F variant in myeloproliferative disorders allowing their reclassification in a new nosological group.
公开/授权文献
- US10364430B2 Identification of a JAK2 mutation in polycythemia vera 公开/授权日：2019-07-30
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