Invention Application
US20140194325A1 RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING INTRACELLULAR BIOLUMINESCENCE RESONANCE ENERGY TRANSFER
审中-公开
通过生物活性剂使用细胞内生物发光共振能量转移识别细胞目标结合
- Patent Title: RECOGNITION OF CELLULAR TARGET BINDING BY A BIOACTIVE AGENT USING INTRACELLULAR BIOLUMINESCENCE RESONANCE ENERGY TRANSFER
- Patent Title (中): 通过生物活性剂使用细胞内生物发光共振能量转移识别细胞目标结合
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Application No.: US14104845Application Date: 2013-12-12
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Publication No.: US20140194325A1Publication Date: 2014-07-10
- Inventor: Carolyn W. Hitko , Thomas Kirkland , Thomas Machleidt , Rachel Friedman Ohana , Matt Robers , Keith Wood
- Applicant: Promega Corporation
- Applicant Address: US WI Madison
- Assignee: Promega Corporation
- Current Assignee: Promega Corporation
- Current Assignee Address: US WI Madison
- Main IPC: G01N33/58
- IPC: G01N33/58 ; G01N33/94
Abstract:
The present invention provides compositions and methods for detection and analysis of intracellular binding of a bioactive agent to a cellular target. In particular, provided herein are bioactive agents tethered to fluorophores, cellular targets fused to bioluminescent reporters, and methods of detecting and analyzing the interaction of bioactive agents with cellular targets therewith.
Public/Granted literature
Information query
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