发明申请
US20140163065A1 PREPARATION AND THERAPEUTIC APPLICATIONS OF (2S, 3R)-N-2-((3-PYRIDINYL)METHYL)-1-AZABICYCLO[2.2.2]OCT-3-YL)-3,5-DIFLUOROBENZAMIDE
有权
(2S,3R)-N-2 - ((3-吡啶基)甲基)-1-亚甲基] [2.2.2] OCT-3-YL)-3,5-二氟硼酰胺的制备和治疗应用
- 专利标题: PREPARATION AND THERAPEUTIC APPLICATIONS OF (2S, 3R)-N-2-((3-PYRIDINYL)METHYL)-1-AZABICYCLO[2.2.2]OCT-3-YL)-3,5-DIFLUOROBENZAMIDE
- 专利标题(中): (2S,3R)-N-2 - ((3-吡啶基)甲基)-1-亚甲基] [2.2.2] OCT-3-YL)-3,5-二氟硼酰胺的制备和治疗应用
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申请号: US13893382申请日: 2013-05-14
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公开(公告)号: US20140163065A1公开(公告)日: 2014-06-12
- 发明人: Merouane Bencherif , Nikolai Fedorov , Terry Hauser , Kristen Jordan , Sharon Rae Letchworth , Anatoly Mazurov , Julio A. Munoz , Jason Speake , Daniel Yohannes
- 申请人: TARGACEPT, INC.
- 申请人地址: US NC Winston-Salem
- 专利权人: TARGACEPT, INC.
- 当前专利权人: TARGACEPT, INC.
- 当前专利权人地址: US NC Winston-Salem
- 主分类号: A61K31/444
- IPC分类号: A61K31/444
摘要:
The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).
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