A RF front-end circuit and a low noise amplifier thereof configured for a receiver are provided. The circuit includes a low noise amplifier and a quadrature passive mixer. The low noise amplifier provides two RF output differential signals to the quadrature passive mixer. The RF signals are down-converted to the differential in-phase baseband signals and the differential quadrature-phase baseband signals. The structure of the RF front-end circuit can avoid the signal and noise interfering between in-phase channel and quadrature-phase channel without using a 25% duty cycle local oscillation generator circuit.