发明申请
- 专利标题: TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS
- 专利标题(中): 三唑啉化合物作为PIM激酶抑制剂
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申请号: US14057882申请日: 2013-10-18
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公开(公告)号: US20140045817A1公开(公告)日: 2014-02-13
- 发明人: Shelley Allen , Laura L. Celeste , T. Gregg Davis , Robert Kirk DeLisle , Julie Marie Hicks , Stefan D. Gross , Erik James Hicken , Leila J. Jackson , Nicholas C. Kallan , Joseph P. Lyssikatos , Fredrik P. Marmsater , Mark C. Munson , Jed Pheneger , Bryson Rast , John E. Robinson , Stephen T. Schlachter , George T. Topalov , A. Dale Wright , Qian Zhao
- 申请人: Array BioPharma Inc.
- 申请人地址: US CO Boulder
- 专利权人: Array BioPharma Inc.
- 当前专利权人: Array BioPharma Inc.
- 当前专利权人地址: US CO Boulder
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; C07D451/06
摘要:
Provided herein is a method of treating a PIM-1 and/or PIM-2 and/or PIM-3 kinase-mediated condition in a mammal, which comprises administering to said mammal a therapeutically effective amount of a compound of Formula I: in which A, B, R1, R1a, R2, R3, R4, R5, R6, and R7 have the meanings given in the specification.
公开/授权文献
- US08987251B2 Triazolopyridine compounds as PIM kinase inhibitors 公开/授权日:2015-03-24
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