发明申请
US20130190365A1 Use of Deferiprone and Methods to Treat and/or Prevent Friedreich Ataxia Resulting from Intracellular Mishandling of Iron
审中-公开
使用去铁酮和方法治疗和/或预防由铁的细胞内不良处理引起的弗里德里希共济失调
- 专利标题： Use of Deferiprone and Methods to Treat and/or Prevent Friedreich Ataxia Resulting from Intracellular Mishandling of Iron
- 专利标题（中）： 使用去铁酮和方法治疗和/或预防由铁的细胞内不良处理引起的弗里德里希共济失调
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申请号： US13755048申请日： 2013-01-31
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公开(公告)号： US20130190365A1公开(公告)日： 2013-07-25
- 发明人: Arnold Munnich , Michael Spino , Ioav Cabantchik
- 申请人： Arnold Munnich , Michael Spino , Ioav Cabantchik
- 主分类号： A61K31/4412
- IPC分类号： A61K31/4412
摘要：
A therapeutically effective amount of deferiprone or deferasirox or physiologically acceptable salts thereof for the prevention, stabilization, treatment, or reversal of iron-induced FRDA disease in patients resulting from mitochondrial iron-induced damage to preferentially reduce the iron stores in the mitochondria. Also for the treatment of other conditions affecting the brain where a key element in the generation of the resultant pathology is the intracellular mishandling of iron.
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