发明申请
- 专利标题： DICARBOXIMIDE DERIVATIVES OF BERBAMINE, THE PREPARATION AND USE THEREOF
- 专利标题（中）： 伯胺的二恶唑衍生物，其制备和用途
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申请号： US13819111申请日： 2011-08-25
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公开(公告)号： US20130158068A1公开(公告)日： 2013-06-20
- 发明人: Rongzhen Xu , Frank Rong , Fuwen Xie , Hongxi Lai
- 申请人： Rongzhen Xu , Frank Rong , Fuwen Xie , Hongxi Lai
- 申请人地址： CN Hangzhou, Zhejiang
- 专利权人： HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD.
- 当前专利权人： HANGZHOU BENSHENG PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： CN Hangzhou, Zhejiang
- 优先权： CNPCT/CN2010/076423 20100827
- 国际申请： PCT/CN11/78905 WO 20110825
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D401/14
摘要：
The present invention relates to a novel dicarboximide derivative of berbamine represented by formula I, including, but not limited to, a phthalimide derivative of berbamine and an aromatic heterocyclic dicarboximide derivative of berbamine, or a pharmaceutically acceptable salt thereof, to a process for preparation of the same, to a pharmaceutical composition comprising said compound and to use thereof in manufacture of an antitumor medicament.
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