Mobile communication devices, having multiple speakers and/or microphones to perform a number of audio functions, for use with mobile devices, are provided. The microphones may be housed within the communication device housing. To compensate for the unwanted signal feedback between the speakers and microphones, acoustic echo cancellation may be implemented to determine the proper distance and relative location between the speakers and microphones. Acoustic echo cancellation removes the echo from voice communications to improve the quality of the sound. The removal of the unwanted signals captured by the microphones may be accomplished by characterizing the audio signal paths from the speakers to the microphones (speaker-to-microphone path distance profile), including the distance and relative location between the speakers and microphones. The optimal distance and relative location between the speakers and microphones is provided to the user to optimize performance.