An integrated portable medical diagnostic system (PMDS) provides easy and convenient access to one or more medical instruments for healthcare practitioners. The PMDS is utilized in an outpatient workflow in which the practitioner generally remains stationary, while patients rotate to and from the practitioner over the course of a medical examination or procedure. The PMDS includes a body including a plurality of compartments, a first compartment defines a first receptacle for a blood pressure monitor, a second compartment adjacent the first compartment defines a second receptacle for an otoscope and an ophthalmoscope, and a third compartment adjacent the second compartment defines a third receptacle for a thermometer.