Integrated circuits with clock generation and distribution circuitry are provided. Integrated circuits may include phase-locked loops configured to generate multiple clock signals that are delayed versions of one another. The clocks signal may be distributed to various regions on an integrated circuit using serially connected clock buffer blocks. Each buffer block may include bidirectional pairs of buffer circuits coupled in parallel. Each buffer circuit may have a first input configured to receive an input clock signal, an output at which a corrected version of the input clock signal is provided (e.g., an output at which an output clock signal with desired duty cycle is provided), a second input that receives a first delayed clock signal for setting the desired duty cycle for the output clock signal, and a third input that receives a second delayed clock signal that is high at least when the first delayed clock signal rises high.