In calibration mode, a clock signal and a data signal are respectively transmitted via a clock lane and a data lane of an MIPI. A test clock signal is provided by adjusting the phase of the clock signal, and a test data signal is provided by adjusting the phase of the data signal. By latching the test data signal according to the test clock signal, a latched data may be acquired for determining an optimized phase relationship corresponding to the clock lane and the data lane. When transmitting the clock signal and the data signal in normal mode, the signal delays of the clock lane and the data lane may be adjusted according to the optimized phase relationship.