Invention Application
US20120190081A1 MICROORGANISM PRODUCING O-PHOSPHOSERINE AND METHOD OF PRODUCING L-CYSTEINE OR DERIVATIVES THEREOF FROM O-PHOSPHOSERINE USING THE SAME
审中-公开
生产O-磷酸的微生物及其使用其的O-磷酸酯生产L-胞嘧啶或其衍生物的方法
- Patent Title: MICROORGANISM PRODUCING O-PHOSPHOSERINE AND METHOD OF PRODUCING L-CYSTEINE OR DERIVATIVES THEREOF FROM O-PHOSPHOSERINE USING THE SAME
- Patent Title (中): 生产O-磷酸的微生物及其使用其的O-磷酸酯生产L-胞嘧啶或其衍生物的方法
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Application No.: US13278102Application Date: 2011-10-20
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Publication No.: US20120190081A1Publication Date: 2012-07-26
- Inventor: Jin Sook CHANG , Jae Hyun JO , Hyun Ae BAE , Byeong Cheol SONG , Sol KIM , Hye Won KIM
- Applicant: Jin Sook CHANG , Jae Hyun JO , Hyun Ae BAE , Byeong Cheol SONG , Sol KIM , Hye Won KIM
- Applicant Address: KR Seoul
- Assignee: CJ CHEILJEDANG CORPORATION
- Current Assignee: CJ CHEILJEDANG CORPORATION
- Current Assignee Address: KR Seoul
- Priority: KR10-2010-0102664 20101020; KR10-2011-0086081 20110826
- Main IPC: C12P13/12
- IPC: C12P13/12 ; C12N1/21
Abstract:
The present invention provides methods for the production of cysteine or derivates thereof by culturing a microorganism having reduced activity of endogenous phosphoserine phosphatase. The O-phosphoserine produced by such an organism can then be reacted with a sulfide in the presence of a sulfydrylase or a microorganism expressing a sulfhydrylase to produce cysteine or a derivative thereof. Microorganisms having the properties noted above are also provided herein.
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