发明申请
US20120149637A1 AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
有权
作为治疗或预防糖尿病的胰蛋白酶IV抑制剂的氨基转移酶
- 专利标题： AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
- 专利标题（中）： 作为治疗或预防糖尿病的胰蛋白酶IV抑制剂的氨基转移酶
-
申请号： US13398887申请日： 2012-02-17
-
公开(公告)号： US20120149637A1公开(公告)日： 2012-06-14
- 发明人: Tesfaye Biftu , Ping Chen , Jason M. Cox , Ann E. Weber
- 申请人： Tesfaye Biftu , Ping Chen , Jason M. Cox , Ann E. Weber
- 主分类号： A61K31/4162
- IPC分类号： A61K31/4162 ; A61K38/28 ; A61P3/10 ; C07D487/04
摘要：
The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
公开/授权文献
信息查询
IPC分类:
