Invention Application
- Patent Title: PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING
- Patent Title (中): 吡格列酮信号肽的吡啶类抑制剂
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Application No.: US13273945Application Date: 2011-10-14
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Publication No.: US20120094980A1Publication Date: 2012-04-19
- Inventor: Janet L. Gunzner , Daniel P. Sutherlin , Mark S. Stanley , Liang Bao , Georgette Castanedo , Rebecca Lalonde , Shumei Wang , Mark E. Reynolds , Scott J. Savage , Kimberly Malesky , Michael S. Dina , Michael F.T. Koehler
- Applicant: Janet L. Gunzner , Daniel P. Sutherlin , Mark S. Stanley , Liang Bao , Georgette Castanedo , Rebecca Lalonde , Shumei Wang , Mark E. Reynolds , Scott J. Savage , Kimberly Malesky , Michael S. Dina , Michael F.T. Koehler
- Main IPC: A61K31/551
- IPC: A61K31/551 ; A61K31/5377 ; C07D401/14 ; A61K31/444 ; C07D213/56 ; A61K31/44 ; C07D409/12 ; A61K31/4436 ; C07D413/12 ; A61K31/4439 ; C07D403/14 ; A61K31/496 ; C07D401/12 ; A61K31/506 ; C07D417/12 ; A61K31/541 ; A61K31/4545 ; C12N5/07 ; A61P35/00 ; A61P9/00 ; C07D413/14
Abstract:
The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.
Information query
