发明申请
- 专利标题： COMPOSITIONS, METHODS AND USES FOR MODULATION OF BRCA 1
- 专利标题（中）： 组合物，调整BRCA的方法和用途1
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申请号： US12937217申请日： 2009-04-13
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公开(公告)号： US20120040896A1公开(公告)日： 2012-02-16
- 发明人: Jeffrey Thomas Holt , Steve Anderson , Andrew Cook Nelson
- 申请人： Jeffrey Thomas Holt , Steve Anderson , Andrew Cook Nelson
- 申请人地址： US CO Denver
- 专利权人： THE REGENTS OF THE UNIVERSITY OF COLORADO
- 当前专利权人： THE REGENTS OF THE UNIVERSITY OF COLORADO
- 当前专利权人地址： US CO Denver
- 国际申请： PCT/US09/40391 WO 20090413
- 主分类号： A61K38/17
- IPC分类号： A61K38/17 ; A61K38/30 ; A61P35/00 ; A61K31/404 ; A61K31/663 ; C07K16/18 ; A61K38/28
摘要：
Embodiments of the present invention generally relate to methods, compositions and uses for diagnosis and treatment of cancer. Certain embodiments report methods and compositions for diagnosing and/or treating a subject having a BRCA1-related cancer or sporadic cancer. Some embodiments disclose treatments that can include, but are not limited to, modulation of BRCA1. In some embodiments, methods for identifying a subject with unstable BRCA1 protein are reported.
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