发明申请
- 专利标题： METHOD OF DEPLETING REGULATORY T CELL
- 专利标题（中）： 去除调节性T细胞的方法
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申请号： US13225811申请日： 2011-09-06
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公开(公告)号： US20120020962A1公开(公告)日： 2012-01-26
- 发明人: Ryuzo UEDA , Kenya SHITARA , Shiro AKINAGA , Rinpei NIWA , Masamichi KOIKE
- 申请人： Ryuzo UEDA , Kenya SHITARA , Shiro AKINAGA , Rinpei NIWA , Masamichi KOIKE
- 申请人地址： JP Tokyo
- 专利权人： KYOWA HAKKO KIRIN CO., LTD
- 当前专利权人： KYOWA HAKKO KIRIN CO., LTD
- 当前专利权人地址： JP Tokyo
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61P41/00 ; A61P35/00 ; A61P31/00 ; A61P37/02 ; A61P29/00
摘要：
The present invention relates to the method for depleting in vivo regulatory T cell, the method for suppressing IL-10 producing activity of regulatory T cell, the method for treating diseases in which pathologic conditions are deteriorated by regulatory T cell and the method for enhancing tumor immunity which comprises administering to a patient a monoclonal antibody which specifically binds to human CC chemokine 4 (CCR4) or the antibody fragment thereof.
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